School of Medicine - Medicine

  • Professor
  • LEE, YUN SONG
  • +82-31-299-6190
  • Medicine Building 5F 715106

Journal Articles

  • (2021)  Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.  Scientific Reports.  11,  1
  • (2020)  Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death.  SCIENCE SIGNALING.  13,  663
  • (2020)  Brain Endothelial P-Glycoprotein Level Is Reduced in Parkinson's Disease via a Vitamin D Receptor-Dependent Pathway.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  21,  22
  • (2020)  Novel Nasal Epithelial Cell Markers of Parkinson's Disease Identified Using Cells Treated with alpha-Synuclein Preformed Fibrils.  JOURNAL OF CLINICAL MEDICINE.  9,  7
  • (2019)  Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson's Disease.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  20,  21
  • (2019)  Cell-Based Screen Using Amyloid Mimic beta 23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of alpha-Synuclein and Huntingtin Aggregates.  MOLECULES AND CELLS.  42,  6
  • (2019)  TTC3 contributes to TGF-beta(1)-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation.  CELL DEATH & DISEASE.  10,  -
  • (2017)  Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models.  ONCOTARGET.  8,  63
  • (2017)  CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  18,  10
  • (2017)  Activation of the ATF2/CREB-PGC-1 alpha pathway by metformin leads to dopaminergic neuroprotection.  ONCOTARGET.  8,  30
  • (2017)  Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson's disease model.  SCIENTIFIC REPORTS.  7, 
  • (2015)  Efficient Mitochondrial Genome Editing by CRISPR/Cas9.  BIOMED RESEARCH INTERNATIONAL. 
  • (2015)  Mitochondrial E3 Ubiquitin Protein Ligase 1 Mediates Cigarette Smoke-Induced Endothelial Cell Death and Dysfunction.  AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY.  54,  2
  • (2012)  Bortezomib Alleviates Experimental Pulmonary Arterial Hypertension.  AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY.  47,  5
  • (2012)  Mesenchymal stem cell-conditioned media recovers lung fibroblasts from cigarette smoke-induced damage.  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY.  302,  9
  • (2011)  YC-1 attenuates hypoxia-induced pulmonary arterial hypertension in mice.  PULMONARY PHARMACOLOGY & THERAPEUTICS.  24,  6
  • (2011)  Bone marrow cells repair cigarette smoke-induced emphysema in rats.  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY.  301,  3
  • (2011)  Cigarrette smoke induces AKT degradation by the ubiquitin proteasome system.  JOURNAL OF BIOLOGICAL CHEMISTRY.  286,  37
  • (2011)  Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells.  RESPIRATORY RESEARCH.  12, 
  • (2010)  Rosiglitazone attenuates hypoxia-induced pulmonary arterial hypertension in rats.  RESPIROLOGY.  15,  4

Patent/Intellectual Property

  • 줄기세포 배양액을 포함하는 폐질환 치료용 조성물(Composition for treating pulmonary disease comprising mesenchymal stem cell-conditioned media).  10-1189655-0000.  20121004.  KOREA, REPUBLIC OF

Conference Paper

  • (2014)  Cigarette Smoke Extract Induces Tetratricopeptide Repeat Domain 3 Through Retinoic Acid Receptor α and Retinoid X Receptor.  제22회 기초의학 학술대회.  KOREA, REPUBLIC OF
  • (2014)  Cigarette Smoke Extract Induces retinoic acid receptor-related orphan receptor alpha (RORα) mediated expression of tetratricopeptide repeat domain 3 (TTC3).  제22회 기초의학 학술대회.  KOREA, REPUBLIC OF
  • (2014)  Tetratrico-peptide repeat domain 3 expression is suppressed by Aryl Hydrocarbon Receptor.  제22회 기초의학 학술대회.  KOREA, REPUBLIC OF
  • (2014)  Tetratricopeptide Repeat Domain 3 Reciprocally Regulates Cellular Retinoic Acid-Binding Protein 2/Fatty Acid-Binding Protein 5, Mediating Retinoic Acid-Induced Cytotoxicity In Breast Cancer Cells: A Strategy To Overcome Retinoic Acid Resistance.  제22회 기초의학 학술대회.  KOREA, REPUBLIC OF
  • (2014)  Cigarette Smoke Extract Induces Expression Of Tetratricopeptide Repeat Domain 3 Through Retinoic Acid Receptor α And Retinoid X Receptor α.  American Thoracid Society International Conference.  UNITED STATES
  • (2014)  Involvement Of Tetratricopeptide Repeat Domain 3 In Pathophysiology Of Pulmonary Fibrosis.  American Thoracic Society International Conference.  UNITED STATES
  • (2012)  Mitochondrial ubiquitin ligase activator of NF-κB (MULAN), an Akt Ubiquitin E3 ligase, Mediates Cigarette Smoke-Induced Endothelial Cell Death and Dysfunction.  American Thoracic Society International Congress 2012.  UNITED STATES
  • (2011)  Cigarette Smoke Causes AKT Degradation Through Ubiquitin Proteasome System In Human Lung Fibroblasts.  Am J Resp Crit Care Med (American Thoracic Society Internation Conference).  UNITED STATES
  • (2010)  FOXP3+ Treg cells induced by repeated low dose gamma irradiation attenuate OVA-induced mouse allergic inflammation.  제62차 대한약리학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2010)  Bortezomib reverses experimental pulmonary hypertension.  제62차 대한약리학회.  KOREA, REPUBLIC OF
  • (2010)  Co-culture of astrocytes and mast cells induces bidirectional cross-talks through CD40 and CD40L interaction.  29th Congress of the European Academy of Allergy and Clinical Immunology.  UNITED KINGDOM
  • (2010)  Signaling pathways in mast cells activated by cross-talk through CD40 and CD40L interaction.  제18회 기초의학학술대회.  KOREA, REPUBLIC OF
  • (2010)  Effects of conditioned media of mesenchymal stem cells on lung fibroblasts damaged by cigarette smoke extract.  American Thoracic Society 2010 International Conference.  UNITED STATES
  • (2009)  Effects of conditioned media of mesenchymal stem cells on lung fibroblasts damaged by cigarette smoke extrct.  제61차 대한약리학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2009)  Expressions of Smad Families in Mast Cell Activation Is Correlated to Mouse Allergic Asthma and Regulation of Smad Proteins by Simvastatin.  American journal of Respiratory and Critical Care Medicine.  UNITED STATES
  • (2009)  Reversal of hypoxia-induced pulmonary arterial hypertension.  American Journal of Respiratory and Critical Care Medicine.  UNITED STATES
  • (2008)  New therapeutic approaches to treat pulmonary arterial hypertension.  Tuberculosis and respiratory diseases.  KOREA, REPUBLIC OF
  • (2008)  New therapeutic approaches to treat pulmonary arterial hypertension.  제60차 대한약리학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2008)  Effects of Adult Stem Cell Transplantation in Smoking-Induced Emphysema.  American thoracic society 2008.  CANADA
  • (2007)  BMT regenerates the damaged lungs of rats exposed to cigarette: therapeutic implication of BMCs in chronic obstructive pulmonary disease.  대한약리학회 추계학술대회.  KOREA, REPUBLIC OF